Biology and Health Technologies

3D Print

Keywords: The 3D printing platform proposes to design and/or to create 3D printed objects.

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3D Print

Artificial Mastication Advanced Machine (AM2)

Keywords: Artificial masticator, mastication, Food oral processing

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Summary

The platform “Articficial masticator” of University Clermont Auvergne has been devised to simulate Food Oral processing in vitro, in either healthy or deficient conditions for mastication while allowing a permanent control of the process. It offers the collection of the whole bolus at any time of the process, and its rheological, granulometrical and/or biochemical characterization.

Biological Sample Irradiation (PAVIRMA)

Keywords: X-ray irradiation, eukaryotic cell cultures, production of mutant animal or plant lines, dosimetry

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Summary

The Pavirma platform is equipped with a self-protected X ray irradiator (PXI320) of 320 KV, 8Gy/min, with a large irradiation chamber for processing large samples (biological or other), and associated biological equipments including a laminar flow hood, a CO2 incubator for the cultivation of eukaryotic cells, a centrifuge and microscopes.

Cell Imaging Service (CICS)

Keywords: Microscopy, Electron Microscopy, Photonic, Cytometry, service delivery

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Summary

Microscopy is an indispensable technique serving materials science and life. All microscopes (photonics, electron, etc.) are complementary with different resolutions to answer scientific questions of researchers and industrials.

Cican'Auv

Keywords: Integrated exploration of immune response polarization (original models of cellular polarization) / Cell cultures 2 and 3D (organoids) / Experimental model of overweight/obesity and/or cancer and/or physical activity / Biological Screening and phytochemistry

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Our research team is specialized in the phenotypic and functional characterization of IMMUNOCOMPETENT CELLS (ICCs) in physio/pathological states particularly in relation to INFLAMMATION and associated chronic diseases such as overweight, obesity and cancer.
In addition, our team has in PHYTOCHEMY in order not only to extract and purify but also to characterize active ingredients of natural origin.

Clermont Confocal Imaging (CLIC)

Keywords: Fluorescence / Laser scanning confocal microscopes/ Spinning Disk / Biology / live cell imaging

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Summary

The CLIC facility (Clermont Imagerie Confocale) provides support in photonic microscopy by supplying the users with several optical systems, mainly confocal microscopes. The facility is available for local public research community and private companies.
Our set-ups allow a broad array of applications : large spectrum of fluorescent dyes, fixed or living cells or tissues, need of a high sensibility or a high resolution or a high acquisition speed.

Cytometry, Sort & Transmission Electronic Microscopy (CYSTEM)

Keywords: Flow cytometry, transmission electron microscopy, enumeration, isolation

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The goal of the Cytometry and Electron Microscopy platform is to give scientists access to an efficient instrumental park dedicated to the structural and functional analysis of biological entities from counting, isolation, cytometry purification approaches to ultra-fine structural analysis by electron microscopy.

Digestive Environment Simulation (Digest-IV)

Keywords: Digestive environment, in vitro model, Nutrition, Health

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The Digestive Environment Simulation Platform proposes to study in vitro the behaviour and/or effects on the digestive environment of any incoming ingredient, microorganism, pre-treatment, formulation, etc., during the digestive process or colic fermentation of Man or the monogastric animal.

Fly Facility

Keywords: Drosophila, transgenesis, genome modifications, CRISPR/Cas9, disease models

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  • Generation of transgenic lines using P-element transformation and site-specific transgenesis
  • CRISPR/CAS9 genome engineering in Drosophila

Galbiopharm

Keywords: Drug delivery development / physicochemical characterization / biopharmaceutical characterization

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The Galbiopharm platform (Galenic and biopharmaceutic characterization) provides the scientific community with a range of state-of-the-art technologies to i) develop conventional or multiparticulate drug delivery systems and ii) characterize in vitro (dissolution, permeability), ex vivo (absorption) and in vivo (pharmacokinetic) physicochemical and biopharmaceutic properties.

Gene Capture

Keywords: Gene capture by hybridization, Metagenomics, Sequencing, Bioinformatics

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Gene capture by hybridization provides access to known or unknown genetic informations for all types of organisms.

High Throughput Genotyping and Sequencing in Auvergne (Gentyane)

Keywords: genotyping, long fragment sequencing, optical mapping, DNA extraction, high throughput, DNA chip

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Summary

The Gentyane platform provides R & D and service for the scientific community and socio-economic partners of a wide range of high-throughput chip genotyping, high-throughput fragmentation sequencing and optical map applications.

In Vivo Imaging Auvergne (IVIA)

Keywords: PET, SPECT, CT, US, MRI, Imaging, in vivo, multimodality

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IVIA platform offers to the academic and industrial scientific community the cutting-edge equipment’s for in vivo imaging. The large spectrum of imaging strategies offers by IVIA platform allows to collect structural and functional information of the small animal to the human.
 

PEPS

Keywords: Performance, evaluation, physical activity, physical fitness, body composition

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The AME2P laboratory is equipped from a platform for assessing physical fitness in healthy, sports or diseased people.

  Platform of Exploration of Metabolism (PFEM)

Keywords: Metabolism/Environment/mass specrometer/NMR spectrometer/statistic studies

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Summary

Platform of "Exploration of Metabolism" (PFEM) is a technological and scientific platform that supports metabolomic and proteomic projects. This INRA-UCA joint infrastructure obtained the French IBiSA labelisation in 2013 and NF X50-900 certification in 2015. PFEM is member of the French National Facility in metabolomics and proteomics (PIA) MetaboHUB (MTH ; www.metabohub.fr) wich aims to develop tools, methodologies and support major projects involving metabolomic and fluxomic approaches.